Lin S, Sin WLW, Koh JJ, Lim F, Wang L, Cao D, Beuerman RW, Ren L, Liu S.*， Semisynthesis and Biological Evaluation of Xanthone Amphiphilics as Selective, Highly Potent Antifungal Agents to Combat Fungal Resistance, J Med Chem. 2017 Dec 28;60(24):10135-10150. (* Corresponding author)
Lin, Shuimu; Koh, Jun-Jie; Aung, Thet Tun; Sin, Wan Ling Wendy; Lim, Fanghui; Wang, Lin; Lakshminarayanan, Rajamani; Zhou, Lei; Tan, Donald T. H.; Cao, Derong; Beuerman, Roger W.; Ren, Li; Liu, Shouping*, Semisynthetic Flavone-Derived Antimicrobials with Therapeutic Potential against Methicillin-Resistant Staphylococcus aureus (MRSA), J. Med. Chem. 2017, Jul 27; 60(14):6152-6165.
Lin, Shuimu; Koh, Jun-Jie; Aung, Thet Tun ; Lim, Fanghui; Li, Jianguo; Zou, Hanxun; Wang, Lin; Lakshminarayanan, Rajamani; Verma, Chandra; Wang, Yingjun; Tan, Donald; Cao, Derong; Beuerman, Roger W.; Ren, Li; Liu, Shouping*, Symmetrically Substituted Xanthone Amphiphiles Combat Gram-positive Bacterial Resistance with Enhanced Membrane Selectivity, J. Med. Chem. 2017 Feb 23; 60(4):1362-1378.
Koh JJ, Zou H, Lin S, Lin H, Soh RT, Lim FH, Koh WL, Li J, Lakshminarayanan R, Verma C, Tan DT, Cao D, Beuerman RW, Liu S.*, Nonpeptidic Amphiphilic Xanthone Derivatives: Structure-Activity Relationship and Membrane-Targeting Properties. J. Med. Chem. 2016 Jan 14;59(1):171-93.
Koh JJ, Lin H, Caroline V, Chew YS, Pang LM, Aung TT, Li J, Lakshminarayanan R, Tan DT, Verma C, Tan AL, Beuerman RW, Liu S.*, N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization. J. Med. Chem. 2015 Aug 27;58(16):6533-48.
Koh JJ, Lin S, Aung TT, Lim F, Zou H, Bai Y, Li J, Lin H, Pang LM, Koh WL, Salleh SM, Lakshminarayanan R, Zhou L, Qiu S, Pervushin K, Verma C, Tan DT, Cao D, Liu S*, Beuerman RW., Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections, J Med Chem. 2015 Jan 22;58(2):739-52
Zou H, Koh JJ, Li J, Qiu S, Aung TT, Lin H, Lakshminarayanan R, Dai X, Tang C, Lim FH, Zhou L, Tan AL, Verma C, Tan DT, Chan HS, Saraswathi P, Cao D, Liu S*, Beuerman RW, Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity. J Med Chem. 2013 Mar 28;56(6):2359-73.
联系邮箱：liusp@gzhmu.edu.cn; liushouping2018@163.com
